Effects of genital ulcer disease and herpes simplex virus type 2 on the efficacy of male circumcision for HIV prevention: Analyses from the Rakai trials.

Effects of genital ulcer disease and herpes simplex virus type 2 on the efficacy of male circumcision for HIV prevention: Analyses from the Rakai trials.

BACKGROUND:Randomized trials show that male circumcision (MC) reduces the incidence of HIV and herpes simplex virus type 2 (HSV-2) infections, and symptomatic genital ulcer disease (GUD). We assessed the role of GUD and HSV-2 in the protection against HIV afforded by MC. METHODS AND FINDINGS:HIV-uni...

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Bibliographic Details
Main Authors: Ronald H Gray, David Serwadda, Aaron A R Tobian, Michael Z Chen, Frederick Makumbi, Tara Suntoke, Godfrey Kigozi, Fred Nalugoda, Boaz Iga, Thomas C Quinn, Lawrence H Moulton, Oliver Laeyendecker, Steven J Reynolds, Xiangrong Kong, Maria J Wawer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC2771764?pdf=render

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http://europepmc.org/articles/PMC2771764?pdf=render

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