The miR-203a Regulatory Network Affects the Proliferation of Chronic Myeloid Leukemia K562 Cells

The miR-203a Regulatory Network Affects the Proliferation of Chronic Myeloid Leukemia K562 Cells

To study the molecular mechanism by which miR-203a affects the development of CML, bioinformatics software was used to predict the upstream transcription factors and downstream target genes of miR-203a. A 5’-rapid amplification of cDNA ends assay was performed to detect gene transcription initiation...

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Bibliographic Details
Main Authors: Jinhua He, Zeping Han, Ziyi An, Yumin Li, Xingyi Xie, Jiabin Zhou, Sihua He, Yubing Lv, Mengling He, Hong Qu, Gexiu Liu, Yuguang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
chronic myeloid leukemia
K562 cells
EGR1
miR-203a
WT1
BMI1
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.616711/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.616711/full

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