A knowledge-based T2-statistic to perform pathway analysis for quantitative proteomic data.

Approaches to identify significant pathways from high-throughput quantitative data have been developed in recent years. Still, the analysis of proteomic data stays difficult because of limited sample size. This limitation also leads to the practice of using a competitive null as common approach; whi...

Full description

Bibliographic Details
Main Authors: En-Yu Lai, Yi-Hau Chen, Kun-Pin Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5493430?pdf=render