Postnatal growth after intrauterine growth restriction alters central leptin signal and energy homeostasis.

Intrauterine growth restriction (IUGR) is closely linked with metabolic diseases, appetite disorders and obesity at adulthood. Leptin, a major adipokine secreted by adipose tissue, circulates in direct proportion to body fat stores, enters the brain and regulates food intake and energy expenditure....

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Bibliographic Details
Main Authors: Bérengère Coupé, Isabelle Grit, Philippe Hulin, Gwenaëlle Randuineau, Patricia Parnet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3264579?pdf=render