Two Insulin Gene Single Nucleotide Polymorphisms Associated with Type 1 Diabetes Risk in the Finnish and Swedish Populations

We have developed high-throughput tests for the detection of the insulin gene region SNPs −23HphI and −2221MspI. The potential of these markers to enhance the efficiency of type 1 diabetes risk screening was then evaluated by analyzing them in Finnish and Swedish populations. Blood spots on filter p...

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Bibliographic Details
Main Authors: Antti-Pekka Laine, Hanna Holmberg, Anita Nilsson, Eva Örtqvist, Minna Kiviniemi, Outi Vaarala, Hans K. Åkerblom, Olli Simell, Mikael Knip, Johnny Ludvigsson, Sten-A. Ivarsson, Karin Larsson, Åke Lernmark, Jorma Ilonen
Format: Article
Language:English
Published: Hindawi Limited 2007-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2007/574363