Optimization of total protein and activity assays for the detection of MMP-12 in induced human sputum
<p>Abstract</p> <p>Background</p> <p>Proteolysis of matrix components, in particular elastin, is a major contributing factor to the development of lung diseases such as emphysema and chronic obstructive pulmonary disease (COPD). MMP-12 (macrophage elastase) is a proteas...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-08-01
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Series: | BMC Pulmonary Medicine |
Online Access: | http://www.biomedcentral.com/1471-2466/10/40 |