Annexin II-dependent actin remodelling evoked by hydrogen peroxide requires the metalloproteinase/sphingolipid pathway

Annexin II-dependent actin remodelling evoked by hydrogen peroxide requires the metalloproteinase/sphingolipid pathway

Actin remodeling is a dynamic process associated with cell shape modification occurring during cell cycle and proliferation. Oxidative stress plays a role in actin reorganization via various systems including p38MAPK. Beside, the mitogenic response evoked by hydrogen peroxide (H2O2) in fibroblasts...

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Bibliographic Details
Main Authors: Christel Cinq-Frais, Christelle Coatrieux, Aude Savary, Romina D’Angelo, Corinne Bernis, Robert Salvayre, Anne Nègre-Salvayre, Nathalie Augé
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Redox Biology
Subjects:
Oxidative stress
Fibroblasts
Smooth muscle cells
Sphingolipids
Actin
Vasculo-proliferative diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231714001293

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http://www.sciencedirect.com/science/article/pii/S2213231714001293

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