Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice
SUMMARY Extracellular signals in development, physiology, homeostasis and disease often act by regulating transcription. Herein we describe a general method and specific resources for determining where and when such signaling occurs in live animals and for systematically comparing the timing and ext...
Main Authors: | , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2012-11-01
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Series: | Disease Models & Mechanisms |
Online Access: | http://dmm.biologists.org/content/5/6/956 |