Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice

SUMMARY Extracellular signals in development, physiology, homeostasis and disease often act by regulating transcription. Herein we describe a general method and specific resources for determining where and when such signaling occurs in live animals and for systematically comparing the timing and ext...

Full description

Bibliographic Details
Main Authors: Palle Serup, Carsten Gustavsen, Tino Klein, Leah A. Potter, Robert Lin, Nandita Mullapudi, Ewa Wandzioch, Angela Hines, Ashley Davis, Christine Bruun, Nina Engberg, Dorthe R. Petersen, Janny M. L. Peterslund, Raymond J. MacDonald, Anne Grapin-Botton, Mark A. Magnuson, Kenneth S. Zaret
Format: Article
Language:English
Published: The Company of Biologists 2012-11-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/5/6/956