Targeted Osmotic Lysis of Highly Invasive Breast Carcinomas Using Pulsed Magnetic Field Stimulation of Voltage-Gated Sodium Channels and Pharmacological Blockade of Sodium Pumps

Targeted Osmotic Lysis of Highly Invasive Breast Carcinomas Using Pulsed Magnetic Field Stimulation of Voltage-Gated Sodium Channels and Pharmacological Blockade of Sodium Pumps

<b>A</b>b<b>stract:</b><b> </b>Concurrent activation of voltage-gated sodium channels (VGSCs) and blockade of Na<sup>+</sup> pumps causes a targeted osmotic lysis (TOL) of carcinomas that over-express the VGSCs. Unfortunately, electrical current bypass...

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Bibliographic Details
Main Authors: Dennis Paul, Paul Maggi, Fabio Del Piero, Steven D. Scahill, Kelly Jean Sherman, Samantha Edenfield, Harry J. Gould
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
targeted osmotic lysis
pulsed magnetic fields
advanced stage carcinoma
sodium channels
sodium pumps
Na+, K+-ATPase
Online Access:https://www.mdpi.com/2072-6694/12/6/1420

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https://www.mdpi.com/2072-6694/12/6/1420

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