Molecular Deregulation of EPAS1 in the Pathogenesis of Esophageal Squamous Cell Carcinoma

Molecular Deregulation of EPAS1 in the Pathogenesis of Esophageal Squamous Cell Carcinoma

Endothelial PAS domain-containing protein 1 (EPAS1) is an angiogenic factor and its implications have been reported in many cancers but not in esophageal squamous cell carcinoma (ESCC). Herein, we aim to examine the genetic and molecular alterations, clinical implications, and functional roles of EP...

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Bibliographic Details
Main Authors: Farhadul Islam, Vinod Gopalan, Simon Law, Alfred K. Lam, Suja Pillai
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
ESCC
EPAS1
cancer prognosis
cancer genetics
mutations
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01534/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01534/full

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