Downregulation of Protein Tyrosine Phosphatase Receptor Type R Accounts for the Progression of Hirschsprung Disease

Downregulation of Protein Tyrosine Phosphatase Receptor Type R Accounts for the Progression of Hirschsprung Disease

Hirschsprung disease (HSCR) is a common developmental disorder of the enteric nervous system (ENS). However, the disease mechanisms have not been fully elucidated. To better understand the etiology of HSCR, the role and mechanism of HSCR associated PTPRR (protein tyrosine phosphatase receptor-type R...

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Bibliographic Details
Main Authors: Jiao Tian, Cheng Zeng, Zhen Tian, Yan Lin, Baoxi Wang, Yongkang Pan, Zhen Shu, Xun Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
hirschsprung’s disease
enteric neural crest cell
enteric nervous system
protein tyrosine phosphatase receptor-type R
glial cell-line derived neurotrophic factor
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00092/full

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https://www.frontiersin.org/article/10.3389/fnmol.2019.00092/full

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