Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A
The calcium-activated chloride channel TMEM16A is a member of a conserved protein family that comprises ion channels and lipid scramblases. Although the structure of the scramblase nhTMEM16 has defined the architecture of the family, it was unknown how a channel has adapted to cope with its distinct...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-05-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/26232 |