Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A

The calcium-activated chloride channel TMEM16A is a member of a conserved protein family that comprises ion channels and lipid scramblases. Although the structure of the scramblase nhTMEM16 has defined the architecture of the family, it was unknown how a channel has adapted to cope with its distinct...

Full description

Bibliographic Details
Main Authors: Cristina Paulino, Yvonne Neldner, Andy KM Lam, Valeria Kalienkova, Janine Denise Brunner, Stephan Schenck, Raimund Dutzler
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/26232