Substance P Depolarizes Lamprey Spinal Cord Neurons by Inhibiting Background Potassium Channels.

Substance P is endogenously released in the adult lamprey spinal cord and accelerates the burst frequency of fictive locomotion. This is achieved by multiple effects on interneurons and motoneurons, including an attenuation of calcium currents, potentiation of NMDA currents and reduction of the reci...

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Bibliographic Details
Main Authors: Carolina Thörn Pérez, Russell H Hill, Sten Grillner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4510128?pdf=render