Environmental and Molecular Drivers of the α-Gal Syndrome

Environmental and Molecular Drivers of the α-Gal Syndrome

The α-Gal syndrome (AGS) is a type of allergy characterized by an IgE antibody (Ab) response against the carbohydrate Galα1-3Galβ1-4GlcNAc-R (α-Gal), which is present in glycoproteins from tick saliva and tissues of non-catarrhine mammals. Recurrent tick bites induce high levels of anti-α-Gal IgE Ab...

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Bibliographic Details
Main Authors: Alejandro Cabezas-Cruz, Adnan Hodžić, Patricia Román-Carrasco, Lourdes Mateos-Hernández, Georg Gerhard Duscher, Deepak Kumar Sinha, Wolfgang Hemmer, Ines Swoboda, Agustín Estrada-Peña, José de la Fuente
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
red meat allergy
food allergy
α-Gal syndrome (AGS)
ticks
IgE
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01210/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01210/full

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