Long pentraxin PTX3 exacerbates pressure overload-induced left ventricular dysfunction.

BACKGROUND: Left ventricular hypertrophy is enhanced by an inflammatory state and stimulation of various cytokines. Pentraxin 3 (PTX3) is rapidly produced in response to inflammatory signals, and high plasma PTX3 levels are seen in patients with heart failure. This study aimed to examine the influen...

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Bibliographic Details
Main Authors: Satoshi Suzuki, Tetsuro Shishido, Akira Funayama, Shunsuke Netsu, Mitsunori Ishino, Tatsuro Kitahara, Toshiki Sasaki, Shigehiko Katoh, Yoichiro Otaki, Tetsu Watanabe, Yoko Shibata, Alberto Mantovani, Yasuchika Takeishi, Isao Kubota
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3553104?pdf=render