Synthetic Hexanucleotides as a Tool to Overcome Excessive Neutrophil Activation Caused by CpG-Containing Oligonucleotides

Mimicking bacterial DNA, synthetic CpG-containing oligodeoxyribonucleotides (CpG-ODNs) have a powerful immunomodulatory potential. Their practical application is mainly associated with the production of vaccines, where they are used as adjuvants, as well as in local antimicrobial therapy. CpG-ODNs a...

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Bibliographic Details
Main Authors: Ekaterina A. Golenkina, Svetlana I. Galkina, Nina G. Dolinnaya, Evgenii A. Arifulin, Yulia M. Romanova, Galina F. Sud’ina
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/10/5/530