Heterogeneous <i>EGFR</i>, <i>CDK4</i>, <i>MDM4</i>, and <i>PDGFRA</i> Gene Expression Profiles in Primary GBM: No Association with Patient Survival

Heterogeneous <i>EGFR</i>, <i>CDK4</i>, <i>MDM4</i>, and <i>PDGFRA</i> Gene Expression Profiles in Primary GBM: No Association with Patient Survival

Background: The prognostic impact of the expression profile of genes recurrently amplified in glioblastoma multiforme (GBM) remains controversial. Methods: We investigated the RNA gene expression profile of epidermal growth factor receptor (<i>EGFR</i>), cyclin-dependent kinase 4 (<i&...

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Bibliographic Details
Main Authors: María González-Tablas, Daniel Arandia, María Jara-Acevedo, Álvaro Otero, Ana-Luisa Vital, Carlos Prieto, Nerea González-Garcia, Ana Belén Nieto-Librero, Herminio Tao, Daniel Pascual, Laura Ruiz, Pablo Sousa, Purificación Galindo-Villardón, Alberto Orfao, María Dolores Tabernero
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cancers
Subjects:
glioblastoma
gene expression profile
amplification
intragenic deletions
heterogeneity
Online Access:https://www.mdpi.com/2072-6694/12/1/231

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https://www.mdpi.com/2072-6694/12/1/231

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