The B7-H1 (PD-L1) T Lymphocyte-Inhibitory Molecule Is Expressed in Breast Cancer Patients with Infiltrating Ductal Carcinoma: Correlation with Important High-Risk Prognostic Factors

The B7-H1 (PD-L1) T Lymphocyte-Inhibitory Molecule Is Expressed in Breast Cancer Patients with Infiltrating Ductal Carcinoma: Correlation with Important High-Risk Prognostic Factors

B7-H1 molecule increases the apoptosis of tumorreactive T lymphocytes and reduces their immunogenicity. Breast cancer is the second most common cause of mortality after lung cancer. Direct evidence linking B7-H1 with cancer has been shown in several malignancies; however, its expression in breast c...

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Bibliographic Details
Main Authors: Hazem Ghebeh, Shamayel Mohammed, Abeer Al-Omair, Amal Qattant, Cynthia Lehe, Ghofran Al-Qudaihi, Naser Elkum, Mohamed Alshabanah, Suad Bin Amer, Asma Tulbah, Dahish Ajarim, Taher Al-Tweigeri, Said Dermime
Format: Article
Language:English
Published: Elsevier 2006-03-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Breast cancer
B7-H1
PD-1-1
tumor-infiltrating lymphocytes
prognostic factors
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558606800473

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http://www.sciencedirect.com/science/article/pii/S1476558606800473

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