Single-Cell Profiling Reveals Divergent, Globally Patterned Immune Responses in Murine Skin Inflammation

Single-Cell Profiling Reveals Divergent, Globally Patterned Immune Responses in Murine Skin Inflammation

Summary: Inflammatory response heterogeneity has impeded high-resolution dissection of diverse immune cell populations during activation. We characterize mouse cutaneous immune cells by single-cell RNA sequencing, after inducing inflammation using imiquimod and oxazolone dermatitis models. We identi...

Full description

Bibliographic Details
Main Authors: Yale Liu, Christopher Cook, Andrew J. Sedgewick, Shuyi Zhang, Marlys S. Fassett, Roberto R. Ricardo-Gonzalez, Paymann Harirchian, Sakeen W. Kashem, Sho Hanakawa, Jacob R. Leistico, Jeffrey P. North, Mark A. Taylor, Wei Zhang, Mao-Qiang Man, Alexandra Charruyer, Nadejda Beliakova-Bethell, Stephen C. Benz, Ruby Ghadially, Theodora M. Mauro, Daniel H. Kaplan, Kenji Kabashima, Jaehyuk Choi, Jun S. Song, Raymond J. Cho, Jeffrey B. Cheng
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:iScience
Subjects:
Immunology
Systems Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220307744

Internet

http://www.sciencedirect.com/science/article/pii/S2589004220307744

Similar Items