Silicone-Acyclovir Controlled Release Devices Suppress Primary Herpes Simplex Virus-2 and Varicella Zoster Virus Infections In Vitro

Following initial infection, herpesviruses retreat into a permanent latent state with periodic reactivation resulting in an enhanced likelihood of transmission and clinical disease. The nucleoside analogue acyclovir reduces clinical symptoms of the three human alpha herpesviruses, HSV-1, HSV-2, and...

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Bibliographic Details
Main Authors: Carol L. Berkower, Nicole M. Johnson, Stephen B. Longdo, Shenika O. McGusty-Robinson, Samantha L. Semenkow, Barry J. Margulies
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Advances in Pharmacological Sciences
Online Access:http://dx.doi.org/10.1155/2013/915159