Silicone-Acyclovir Controlled Release Devices Suppress Primary Herpes Simplex Virus-2 and Varicella Zoster Virus Infections In Vitro
Following initial infection, herpesviruses retreat into a permanent latent state with periodic reactivation resulting in an enhanced likelihood of transmission and clinical disease. The nucleoside analogue acyclovir reduces clinical symptoms of the three human alpha herpesviruses, HSV-1, HSV-2, and...
Main Authors: | Carol L. Berkower, Nicole M. Johnson, Stephen B. Longdo, Shenika O. McGusty-Robinson, Samantha L. Semenkow, Barry J. Margulies |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2013-01-01
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Series: | Advances in Pharmacological Sciences |
Online Access: | http://dx.doi.org/10.1155/2013/915159 |
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