Opuntioside, opuntiol and its metallic nanoparticles attenuate adjuvant-induced arthritis: Novel suppressors of Toll-like receptors -2 and -4

Opuntioside, opuntiol and its metallic nanoparticles attenuate adjuvant-induced arthritis: Novel suppressors of Toll-like receptors -2 and -4

Rheumatoid arthritis (RA) is a chronic autoimmune disease of synovial inflammation and joint destruction. This study reports anti-arthritic potential of opuntioside-I opuntiol, and its gold and silver nanoparticles (NPs) against Complete Freund’s Adjuvant (CFA)-induced arthritic rats. The mechanisti...

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Bibliographic Details
Main Authors: Talat Roome, Sabahat Aziz, Anam Razzak, Zara Aslam, Lubna, Khawar Saeed Jamali, Bushra Sikandar, Tehseen Fatima, Lubna Abidi, Muhammad Imran, Shaheen Faizi, Muhammad Raza Shah
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Opuntiol
Opuntioside
Metals nanoparticles
Cytokines
TLRs expression
Arthritis
Online Access:http://www.sciencedirect.com/science/article/pii/S075333221835813X

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http://www.sciencedirect.com/science/article/pii/S075333221835813X

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