The Purine Bias of Coding Sequences is Determined by Physicochemical Constraints on Proteins

For this report, we analyzed protein secondary structures in relation to the statistics of three nucleotide codon positions. The purpose of this investigation was to find which properties of the ribosome, tRNA or protein level, could explain the purine bias (Rrr) as it is observed in coding DNA. We...

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Bibliographic Details
Main Authors: Miguel Ponce De Leon, Antonio Basilio De Miranda, Fernando Alvarez-Valin, Nicolas Carels
Format: Article
Language:English
Published: SAGE Publishing 2014-01-01
Series:Bioinformatics and Biology Insights
Online Access:https://doi.org/10.4137/BBI.S13161