Effect of BRCA mutational status on survival outcome in advanced-stage high-grade serous ovarian cancer

Effect of BRCA mutational status on survival outcome in advanced-stage high-grade serous ovarian cancer

Abstract Objective To evaluate impact of germline BRCA mutational status on prognosis in patients with advanced ovarian cancer. Methods A total of 128 patients diagnosed with FIGO stage III-IV high-grade serous ovarian cancer (HGSOC) between 2008 and 2017 and underwent BRCA1/2 gene testing at the ti...

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Bibliographic Details
Main Authors: Se Ik Kim, Maria Lee, Hee Seung Kim, Hyun Hoon Chung, Jae-Weon Kim, Noh Hyun Park, Yong-Sang Song
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Ovarian Research
Subjects:
Genital neoplasms, female
Ovarian neoplasms
High-grade serous carcinoma
BRCA1/2 germline mutation
Clinical outcome
Survival outcome
Online Access:http://link.springer.com/article/10.1186/s13048-019-0511-7

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http://link.springer.com/article/10.1186/s13048-019-0511-7

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