Genetic determinants influencing human serum metabolome among African Americans.

Phenotypes proximal to gene action generally reflect larger genetic effect sizes than those that are distant. The human metabolome, a result of multiple cellular and biological processes, are functional intermediate phenotypes proximal to gene action. Here, we present a genome-wide association study...

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Bibliographic Details
Main Authors: Bing Yu, Yan Zheng, Danny Alexander, Alanna C Morrison, Josef Coresh, Eric Boerwinkle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3952826?pdf=render