Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.

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Translating a set of disease regions into insight about pathogenic mechanisms requires not only the ability to identify the key disease genes within them, but also the biological relationships among those key genes. Here we describe a statistical method, Gene Relationships Among Implicated Loci (GRA...

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Bibliographic Details
Main Authors: Soumya Raychaudhuri, Robert M Plenge, Elizabeth J Rossin, Aylwin C Y Ng, International Schizophrenia Consortium, Shaun M Purcell, Pamela Sklar, Edward M Scolnick, Ramnik J Xavier, David Altshuler, Mark J Daly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2694358?pdf=render

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http://europepmc.org/articles/PMC2694358?pdf=render

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