IL-17 produced during Trypanosoma cruzi infection plays a central role in regulating parasite-induced myocarditis.

IL-17 produced during Trypanosoma cruzi infection plays a central role in regulating parasite-induced myocarditis.

BACKGROUND: Chagas disease is a neglected disease caused by the intracellular parasite Trypanosoma cruzi. Around 30% of the infected patients develop chronic cardiomyopathy or megasyndromes, which are high-cost morbid conditions. Immune response against myocardial self-antigens and exacerbated Th1 c...

Full description

Bibliographic Details
Main Authors: Paulo Marcos da Matta Guedes, Fredy R S Gutierrez, Flavia L Maia, Cristiane M Milanezi, Grace K Silva, Wander R Pavanelli, João S Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2821906?pdf=render

Internet

http://europepmc.org/articles/PMC2821906?pdf=render

Similar Items