Potential relevance of alpha(1)-adrenergic receptor autoantibodies in refractory hypertension.

Potential relevance of alpha(1)-adrenergic receptor autoantibodies in refractory hypertension.

Agonistic autoantibodies directed at the alpha(1)-adrenergic receptor (alpha(1)-AAB) have been described in patients with hypertension. We implied earlier that alpha(1)-AAB might have a mechanistic role and could represent a therapeutic target.To pursue the issue, we performed clinical and basic stu...

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Bibliographic Details
Main Authors: Katrin Wenzel, Hannelore Haase, Gerd Wallukat, Wolfgang Derer, Sabine Bartel, Volker Homuth, Florian Herse, Norbert Hubner, Herbert Schulz, Marion Janczikowski, Carsten Lindschau, Christoph Schroeder, Stefan Verlohren, Ingo Morano, Dominik N Muller, Friedrich C Luft, Rainer Dietz, Ralf Dechend, Peter Karczewski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2580028?pdf=render

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http://europepmc.org/articles/PMC2580028?pdf=render

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