In vitro evaluation of double carbapenem and colistin combinations against OXA-48, NDM carbapenemase-producing colistin-resistant Klebsiella pneumoniae strains

In vitro evaluation of double carbapenem and colistin combinations against OXA-48, NDM carbapenemase-producing colistin-resistant Klebsiella pneumoniae strains

Abstract Background Treatment of pandrug-resistant isolates often necessitates combination therapy. Checkerboard synergy and time-killing assay tests were performed to evaluate the benefits of a triple combination with meropenem, ertapenem, and colistin against 10 colistin-resistant K. pneumoniae cl...

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Bibliographic Details
Main Authors: Fatma Erdem, Ayham Abulaila, Zerrin Aktas, Oral Oncul
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Antimicrobial Resistance and Infection Control
Subjects:
Colistin-resistant Klebsiella pneumoniae
Time-kill assay
OXA-181
OXA-48
NDM
Whole genome analysis
Online Access:http://link.springer.com/article/10.1186/s13756-020-00727-4

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http://link.springer.com/article/10.1186/s13756-020-00727-4

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