Induction of Apoptosis and Cytotoxicity by Isothiocyanate Sulforaphene in Human Hepatocarcinoma HepG2 Cells

Glucoraphenin, a glucosinolate present in large quantities in radish is hydrolysed by myrosinase to form the isothiocyanate sulforaphene, which is believed to be responsible for its chemopreventive activity; however, the underlying mechanisms of action have not been investigated, particularly in hum...

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Bibliographic Details
Main Authors: Saie Brindha Kntayya, Muhammad Din Ibrahim, Nooraini Mohd Ain, Renato Iori, Costas Ioannides, Ahmad Faizal Abdull Razis
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Nutrients
Subjects:
Online Access:http://www.mdpi.com/2072-6643/10/6/718