Spatial and functional heterogeneities shape collective behavior of tumor-immune networks.
Tumor growth involves a dynamic interplay between cancer cells and host cells, which collectively form a tumor microenvironmental network that either suppresses or promotes tumor growth under different conditions. The transition from tumor suppression to tumor promotion is mediated by a tumor-induce...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-04-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4408028?pdf=render |