Dynamic Emergence of Mismatch Repair Deficiency Facilitates Rapid Evolution of Ceftazidime-Avibactam Resistance in Pseudomonas aeruginosa Acute Infection
Antimicrobial resistance in bacteria represents one of the most consequential problems in modern medicine, and its emergence and spread threaten to compromise central advances in the treatment of infectious diseases. Ceftazidime-avibactam (CZA) belongs to a new class of broad-spectrum beta-lactam/be...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2019-09-01
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Series: | mBio |
Subjects: | |
Online Access: | https://doi.org/10.1128/mBio.01822-19 |