Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood

Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood

Abstract Corline Heparin Conjugate (CHC), a compound of multiple unfractionated heparin chains, coats cells with a glycocalyx-like layer and may inhibit (xeno)transplant-associated activation of the plasma cascade systems. Here, we investigated the use of CHC to protect WT and genetically modified (...

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Bibliographic Details
Main Authors: Anjan K. Bongoni, Evelyn Salvaris, Sofia Nordling, Nikolai Klymiuk, Eckhard Wolf, David L. Ayares, Robert Rieben, Peetra U. Magnusson, Peter J. Cowan
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04898-w

Internet

https://doi.org/10.1038/s41598-017-04898-w

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