New Approaches to Improving Bendamustine Microractor Synthesis

Introduction. The chlorination reaction in the synthesis of the substance of bendamustine hydrochloride is a complex process. The presence of active adverse reactions makes scaling difficult.Aim. Improving the performance of the technology for producing bendamustine ethyl ester in a flow microreacto...

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Bibliographic Details
Main Authors: A. L. Moldavsky, A. M. Yurakov, B. Yu. Lalaev, I. A. Fridman
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2020-02-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/758