New Morphiceptin Peptidomimetic Incorporating (1<i>S</i>,2<i>R</i>,3<i>S</i>,4<i>S</i>,5<i>R</i>)-2-Amino-3,4,5-trihydroxycyclopen-tane-1-carboxylic Acid: Synthesis and Structural Study

New Morphiceptin Peptidomimetic Incorporating (1<i>S</i>,2<i>R</i>,3<i>S</i>,4<i>S</i>,5<i>R</i>)-2-Amino-3,4,5-trihydroxycyclopen-tane-1-carboxylic Acid: Synthesis and Structural Study

We present the synthesis and structural study of a new peptidomimetic of morphiceptin, which can formally be considered as the result of the replacement of the central proline residue of this natural analgesic drug with a subunit of (1<i>S</i>,2<i>R</i>,3<i>S</i>,...

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Bibliographic Details
Main Authors: Raquel Soengas, Marcos Lorca, Begoña Pampín, Víctor M. Sánchez-Pedregal, Ramón J. Estévez, Juan C. Estévez
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
morphiceptin
alicyclic β-amino acids
peptidomimetics
nitro sugars
analgesic
Online Access:https://www.mdpi.com/1420-3049/25/11/2574

Internet

https://www.mdpi.com/1420-3049/25/11/2574

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