Proteomic Analysis in Morquio A Cells Treated with Immobilized Enzymatic Replacement Therapy on Nanostructured Lipid Systems

Proteomic Analysis in Morquio A Cells Treated with Immobilized Enzymatic Replacement Therapy on Nanostructured Lipid Systems

Morquio A syndrome, or mucopolysaccharidosis type IVA (MPS IVA), is a lysosomal storage disease due to mutations in the N-acetylgalactosamine-6-sulfatase (<i>GALNS</i>) gene. Systemic skeletal dysplasia and the related clinical features of MPS IVA are due to disruption of cartilage and i...

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Bibliographic Details
Main Authors: J. Víctor Álvarez, Susana B. Bravo, María García-Vence, María J. De Castro, Asteria Luzardo, Cristóbal Colón, Shunji Tomatsu, Francisco J. Otero-Espinar, María L. Couce
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
enzyme replacement therapy
lysosomal disorders
nanoparticles
proteomics
Online Access:https://www.mdpi.com/1422-0067/20/18/4610

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https://www.mdpi.com/1422-0067/20/18/4610

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