Perturbation-expression analysis identifies RUNX1 as a regulator of human mammary stem cell differentiation.
The search for genes that regulate stem cell self-renewal and differentiation has been hindered by a paucity of markers that uniquely label stem cells and early progenitors. To circumvent this difficulty we have developed a method that identifies cell-state regulators without requiring any markers o...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-04-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4404314?pdf=render |