Perturbation-expression analysis identifies RUNX1 as a regulator of human mammary stem cell differentiation.

The search for genes that regulate stem cell self-renewal and differentiation has been hindered by a paucity of markers that uniquely label stem cells and early progenitors. To circumvent this difficulty we have developed a method that identifies cell-state regulators without requiring any markers o...

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Bibliographic Details
Main Authors: Ethan S Sokol, Sandhya Sanduja, Dexter X Jin, Daniel H Miller, Robert A Mathis, Piyush B Gupta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4404314?pdf=render