Hepatocyte-Specific Deletion of Mouse Lamin A/C Leads to Male-Selective SteatohepatitisSummary

Hepatocyte-Specific Deletion of Mouse Lamin A/C Leads to Male-Selective SteatohepatitisSummary

Background & Aims: Lamins are nuclear intermediate filament proteins that comprise the major components of the nuclear lamina. Mutations in LMNA, which encodes lamins A/C, cause laminopathies, including lipodystrophy, cardiomyopathy, and premature aging syndromes. However, the role of lamins in...

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Main Authors: Raymond Kwan, Graham F. Brady, Maria Brzozowski, Sujith V. Weerasinghe, Hope Martin, Min-Jung Park, Makayla J. Brunt, Ram K. Menon, Xin Tong, Lei Yin, Colin L. Stewart, M. Bishr Omary
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X17301030

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http://www.sciencedirect.com/science/article/pii/S2352345X17301030

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