Bone Marrow Mesenchymal Stromal Cells Isolated from Multiple Sclerosis Patients have Distinct Gene Expression Profile and Decreased Suppressive Function Compared with Healthy Counterparts

Bone Marrow Mesenchymal Stromal Cells Isolated from Multiple Sclerosis Patients have Distinct Gene Expression Profile and Decreased Suppressive Function Compared with Healthy Counterparts

Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system, due to an immune reaction against myelin proteins. Multipotent mesenchymal stromal cells (MSCs) present immunosuppressive effects and have been used for the treatment of autoimmune diseases. In our st...

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Bibliographic Details
Main Authors: Gislane L. V. De Oliveira Ph.D., Kalil W. A. De Lima, Amanda M. Colombini, Daniel G. Pinheiro, Rodrigo A. Panepucci, Patrícia V. B. Palma, Doralina G. Brum, Dimas T. Covas, Belinda P. Simões, Maria C. De Oliveira, Eduardo A. Donadi, Kelen C. R. Malmegrim
Format: Article
Language:English
Published: SAGE Publishing 2015-02-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368913X675142

Internet

https://doi.org/10.3727/096368913X675142

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