Molecular Evolution of the VP1 Gene in Human Norovirus GII.4 Variants in 1974–2015

Molecular Evolution of the VP1 Gene in Human Norovirus GII.4 Variants in 1974–2015

Human norovirus (HuNoV) is a leading cause of viral gastroenteritis worldwide, of which GII.4 is the most predominant genotype. Unlike other genotypes, GII.4 has created various variants that escaped from previously acquired immunity of the host and caused repeated epidemics. However, the molecular...

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Bibliographic Details
Main Authors: Takumi Motoya, Koo Nagasawa, Yuki Matsushima, Noriko Nagata, Akihide Ryo, Tsuyoshi Sekizuka, Akifumi Yamashita, Makoto Kuroda, Yukio Morita, Yoshiyuki Suzuki, Nobuya Sasaki, Kazuhiko Katayama, Hirokazu Kimura
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Microbiology
Subjects:
bioinformatics
GII.4
molecular evolution
Norovirus
VP1
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02399/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.02399/full

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