SANS (USH1G) Molecularly Links the Human Usher Syndrome Protein Network to the Intraflagellar Transport Module by Direct Binding to IFT-B Proteins

SANS (USH1G) Molecularly Links the Human Usher Syndrome Protein Network to the Intraflagellar Transport Module by Direct Binding to IFT-B Proteins

The human Usher syndrome (USH) is a retinal ciliopathy, characterized by profound congenital deafness, variable vestibular dysfunction and pre-pubertal onset of retinitis pigmentosa. In the effected sensory cells, USH protein networks are assumed to function in ciliary transport processes. The USH1G...

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Bibliographic Details
Main Authors: Nasrin Sorusch, Adem Yildirim, Barbara Knapp, Julia Janson, Wiebke Fleck, Caroline Scharf, Uwe Wolfrum
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Usher syndrome
USH1G
IFT
ciliary transport
photoreceptor cell
primary cilia
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00216/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2019.00216/full

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