Dietary α-Linolenic Acid Counters Cardioprotective Dysfunction in Diabetic Mice: Unconventional PUFA Protection

Dietary α-Linolenic Acid Counters Cardioprotective Dysfunction in Diabetic Mice: Unconventional PUFA Protection

Whether dietary omega-3 (n-3) polyunsaturated fatty acid (PUFA) confers cardiac benefit in cardiometabolic disorders is unclear. We test whether dietary -linolenic acid (ALA) enhances myocardial resistance to ischemia-reperfusion (I-R) and responses to ischemic preconditioning (IPC) in type 2 diabet...

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Bibliographic Details
Main Authors: Jake S. Russell, Tia A. Griffith, Saba Naghipour, Jelena Vider, Eugene F. Du Toit, Hemal H. Patel, Jason N. Peart, John P. Headrick
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Nutrients
Subjects:
-linolenic acid
n-3 PUFA
diabetes
cardioprotection
caveolae
caveolins
Online Access:https://www.mdpi.com/2072-6643/12/9/2679

Internet

https://www.mdpi.com/2072-6643/12/9/2679

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