Quantitative optical nanophysiology of Ca2+ signaling at inner hair cell active zones

Quantitatively studying components of the presynapse requires high resolution optical methods. Here the authors use confocal microscopy as well as 2D- and 3D-STED nanoscopy to quantify the number and activity of active zone Ca2+ channels in inner hair cells.

Bibliographic Details
Main Authors: Jakob Neef, Nicolai T. Urban, Tzu-Lun Ohn, Thomas Frank, Philippe Jean, Stefan W. Hell, Katrin I. Willig, Tobias Moser
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02612-y