MiR-124-3p/B4GALT1 axis plays an important role in SOCS3-regulated growth and chemo-sensitivity of CML

MiR-124-3p/B4GALT1 axis plays an important role in SOCS3-regulated growth and chemo-sensitivity of CML

Abstract Background Abnormal expression of SOCS3 has been implicated in myeloproliferative neoplasms, but the role of SOCS3 in the pathogenesis of leukemia remains largely unknown. Here, we examined the function of SOCS3 in the growth and chemo-sensitivity of chronic myeloid leukemia (CML) and explo...

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Bibliographic Details
Main Authors: Yu-xiao Liu, Li Wang, Wen-jia Liu, Hai-tao Zhang, Jing-hui Xue, Zhi-wen Zhang, Chun-ji Gao
Format: Article
Language:English
Published: BMC 2016-08-01
Series:Journal of Hematology & Oncology
Subjects:
SOCS3
miR-124
B4GALT1
Leukemogenesis
Chemo-sensitivity
Online Access:http://link.springer.com/article/10.1186/s13045-016-0300-3

Internet

http://link.springer.com/article/10.1186/s13045-016-0300-3

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