Hepatic Fatty Acid Oxidation Restrains Systemic Catabolism during Starvation
The liver is critical for maintaining systemic energy balance during starvation. To understand the role of hepatic fatty acid β-oxidation on this process, we generated mice with a liver-specific knockout of carnitine palmitoyltransferase 2 (Cpt2L−/−), an obligate step in mitochondrial long-chain fat...
Main Authors: | Jieun Lee, Joseph Choi, Susanna Scafidi, Michael J. Wolfgang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-06-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221112471630660X |
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