Mitochondrial Bioenergetics Is Altered in Fibroblasts from Patients with Sporadic Alzheimer's Disease

The identification of an early biomarker to diagnose Alzheimer's disease (AD) remains a challenge. Neuropathological studies in animal and AD patients have shown that mitochondrial dysfunction is a hallmark of the development of the disease. Current studies suggest the use of peripheral tissues...

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Bibliographic Details
Main Authors: María J. Pérez, Daniela P. Ponce, Cesar Osorio-Fuentealba, Maria I. Behrens, Rodrigo A. Quintanilla
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00553/full