Local inflammation exacerbates the severity of Staphylococcus aureus skin infection.

Staphylococcus aureus is the leading cause of skin infections. In a mouse model of S. aureus skin infection, we found that lesion size did not correlate with bacterial burden. Athymic nude mice had smaller skin lesions that contained lower levels of myeloperoxidase, IL-17A, and CXCL1, compared with...

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Bibliographic Details
Main Authors: Christopher P Montgomery, Melvin D Daniels, Fan Zhao, Brad Spellberg, Anita S Chong, Robert S Daum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3702601?pdf=render