Allergen Immunotherapy–Induced Immunoglobulin G4 Reduces Basophil Activation in House Dust Mite–Allergic Asthma Patients

Allergen Immunotherapy–Induced Immunoglobulin G4 Reduces Basophil Activation in House Dust Mite–Allergic Asthma Patients

It is unclear if allergen immunotherapy (AIT) can reduce allergy effector cell activation. We evaluated the basophil response during Dermatophagoides pteronyssinus (Der p) subcutaneous immunotherapy (SCIT) and its relationship to allergen-specific immunoglobulin G4 (sIgG4) in allergic rhinitis and/o...

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Bibliographic Details
Main Authors: Mulin Feng, Xiaohui Zeng, Qiujuan Su, Xu Shi, Mo Xian, Rundong Qin, Jing Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
asthma
rhinitis
allergen immunotherapy
basophil activation test
serum specific immunoglobulin G4 (IgG4)
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00030/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00030/full

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