NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis.

Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and adaptive immune responses. In the present study, we demonstrate that nucleotide-binding oligomerizat...

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Bibliographic Details
Main Authors: Gerben Ferwerda, Stephen E Girardin, Bart-Jan Kullberg, Lionel Le Bourhis, Dirk J de Jong, Dennis M L Langenberg, Reinout van Crevel, Gosse J Adema, Tom H M Ottenhoff, Jos W M Van der Meer, Mihai G Netea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.0010034