CPT1A/2-Mediated FAO Enhancement—A Metabolic Target in Radioresistant Breast Cancer
Tumor cells, including cancer stem cells (CSCs) resistant to radio- and chemotherapy, must enhance metabolism to meet the extra energy demands to repair and survive such genotoxic conditions. However, such stress-induced adaptive metabolic alterations, especially in cancer cells that survive radioth...
Main Authors: | Shujun Han, Ryan Wei, Xiaodi Zhang, Nian Jiang, Ming Fan, Jie Hunter Huang, Bowen Xie, Lu Zhang, Weili Miao, Ashley Chen-Ping Butler, Matthew A. Coleman, Andrew T. Vaughan, Yinsheng Wang, Hong-Wu Chen, Jiankang Liu, Jian Jian Li |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-11-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fonc.2019.01201/full |
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